Peptiva Review

About Peptiva

Peptiva Review

Alright, how many of us have trouble sleeping and wake up feeling groggy and tired? Let’s not forget those digestive issues some of us have been living with for several years. 

Well, I don’t want to be the bearers of bad news but these issues are not normal. If you need some help in these areas, then you want to keep reading this Peptiva review. 

Marketed as night-time probiotics, Peptiva products are doctor-formulated for people who suffer from digestive and sleep issues. Now, it’s uncommon to hear a supplement helping with digestion and sleep at the same time, isn’t it? 

Well, that’s where the uniqueness lies, helping the brand gain 15.2k Instagram followers. This company offers a clinically validated combination of probiotics and calming ingredients so you can get a restful sleep. 

In this Peptiva review, I will dig deep into its ingredients, uses, benefits, possible downsides, customer ratings, promotions, and all other details you are looking for to decide if this product is for you. 

Overview of Peptiva

Peptiva Review

In 2017, Peptiva was formulated with the help of Dr. David Katz, former director and co-founder of the Yale-Griffin Prevention Research Center. He wanted to create a probiotic that was a step ahead of the regular probiotics on the market. That’s when he created these nighttime probiotics

While gut microbes have been stealing the limelight lately, the impacts of poor quality sleep can’t be forgotten. Improving both will be a boost to your health and longevity. 

Basically, while you are sleeping, your digestive system is resting as well, which Dr. Katz says is the perfect time to reestablish the balance between your good and bad bacteria. And the cherry on top is that all this happens while you are getting a restful night of sleep. This is what Peptiva aims to do. 

Before I get into more details in this Peptiva review, it’s important to talk about those trillions of bacteria that live in your gut. Your gut has both good and bad bacteria, but we want the good bacteria and their powers to shine over the bad ones.

Why you may ask? Well, the good ones help with our immunity, digestion, and mood. The bad ones are disease-promoting. 

Now, you may be wondering what causes them to become unbalanced? The answer lies in the type of lifestyle you live, the food you eat, the stress you have and how you deal with it, pollution, and the quality and amount of sleep you get. The good news is that Peptiva has the sleep aspect covered, restoring your gut at the same time. 

Another uniqueness of Peptiva lies in the fact that it goes through a special Tri-Phase Dehydration process that guarantees all the bacteria stay alive and active when they reach your gut. This guarantee means a lot because while a bottle may claim to have billions of bacteria in a capsule, not all of them reach the gut intact. 

Peptiva products are manufactured in the U.K under strict FDA guidelines at a cGMP-approved facility. 

Peptiva Review

Before I dissect its ingredients, let’s take a quick look at some highlights: 


  • Convenient way to achieve good digestive health and get a restful sleep 
  • Complete 30-day money-back guarantee 
  • Offer a 15-day trial
  • Non-GMO
  • Guaranteed potency to reach the gut intact 
  • Ingredients backed by clinical evidence 
  • 6 clinically validated probiotic strains 
  • Takes 30 minutes to see changes in relaxation and sleep

Now that you have a basic understanding of the brand, my Peptiva review will dig deeper into the ingredients of their three products and how they work. 

Peptiva + Sleep Support Review

Peptiva + Sleep Support Review
Peptiva + Sleep Support

One of their top sellers, Peptiva + Sleep Support is pretty self-explanatory thanks to its name. It consists of a proprietary blend of probiotics along with soothing sleep ingredients such as GABA, melatonin, and valerian extract.

Ingredients Label

Wondering what each calming ingredient does? I’m just about to explain it, so you know exactly what you are taking.

The proprietary probiotic blend contains 6 strains of live and active bacteria which are shown to be clinically effective at the right dosage.


What’s unique about the GABA in Peptiva is that it is produced using a natural fermentation process. As shown in this study, GABA is a neurotransmitter produced in the brain known to promote relaxation and restful sleep. How does it do that? GABA increases the alpha waves in our brain which are known to put us in a calm state.


Now, melatonin is something you have heard about right? It’s basically a hormone produced at night which promotes sleep. Its production increases with darkness. Peptiva has cleverly included two forms of melatonin: an immediate-release to help you fall asleep faster and a delayed-release to keep you sleeping.

Valerian Root 

This herb has been used in ancient remedies and has been proven clinically to promote relaxation and sleep.

Nutritional Value

The total number of bacteria is 26 Billion CFU. What is a CFU? Basically, it stands for colony forming units and is a complicated way of saying the number of live and active bacteria in the supplement.

Now, remember that the number of bacteria labeled on the bottle is not necessarily how much will end up in our gut. But, Peptiva promises through its proprietary process that the probiotics present in this product are protected against damage

There is 100 mg of GABA, 50 mg of valerian root, 0.75 mg of melatonin immediate-release, and 0.75 mg of melatonin delayed-release. 


Let’s look at some of the clinically proven benefits of these probiotics: 

  1. Improved bowel habits after 12 weeks such as constipation
  2. Improved digestive symptoms like bloating and abdominal discomfort after 8 weeks 

Basically, the benefits of this product lie in improving digestive symptoms like bloating, gas, and constipation. As far as sleep is concerned, it is known to promote relaxation and sleep as it is working on the digestive system.

How Does it Work

This is the main Peptiva product that perfectly addresses your sleep and digestive issues. The 6 strains of probiotics calm your stomach as the GABA, melatonin, and valerian root all work together to help you get to sleep, promoting relaxation.

Melatonin in particular is useful in this supplement as there are two types used here, one that helps you get to sleep and another that will keep you sleeping. That way, your head and your stomach will feel renewed when you wake up.

If you are wondering how and when to take this product, then keep reading this Peptiva review.

How to Take and Dosage

Basically, the best time to take it is 30 to 60 minutes before bed with a small snack to prevent digestive irritation. The instructions say to take one capsule with water every day. 

Wondering how much it costs? This package retails for $60 for a 30-day supply on their official website. Before you hesitate to buy this product, remember that it is a 2-in-1 product combining probiotics and sleep support.

Now, this Peptiva review will discuss the second product which focuses more on calming.

Peptiva Advanced Digestive Relief Review

Peptiva Advanced Digestive Relief Review
Peptiva Advanced Digestive Relief

Peptiva Advanced Digestive Relief is also basically a nighttime probiotic with an added calming concoction. The calming effect is brought on by L-theanine, GABA, and lemon balm extract.

How does it differ from Peptiva + Sleep? In this product, there are four strains of bacteria totaling 50 billion CFU. Also, the calming ingredients promote a state of zen. I agree that this calming effect can lead to a night of more restful sleep, but this product is not directly meant to help sleep.

Ingredients Label

You’ll find four strains of probiotics in this product, totaling 50 billion CFU. But what about those claiming ingredients? I have already spoken about GABA and its relaxation benefits. So let’s talk about the other two ingredients:

L-theanine (200 mg): Found in green tea, this amino acid is known to relax you while increasing your focus at the same time. It can help relieve some anxiety and stress at therapeutic doses, as this study found.

Lemon balm extract (75 mg): This herb can also promote a state of relaxation. 

Inactive ingredients include Hypromellose, microcrystalline cellulose, acacia gum, maltodextrin, silica, magnesium stearate, titanium dioxide, FD&C Blue #1, and FD&C Yellow #6.

Nutritional Value

This product contains 100mg of GABA along with 200mg of L-theanine and 75mg of lemon balm extract. In terms of probiotics, there are 4 strains of bacteria totaling 50 Billion CFUs.


GABA is a very useful neurotransmitter that promotes relaxation. Now take that relaxation and boost it up thanks to the combined action of the other ingredients that can help calm your nerves at the end of a long day. How about combining this with some candles or a book? Oh, that sounds relaxing.

How Does it Work 

Just like the Peptiva + Sleep product, this product works in a similar fashion. The probiotic helps promote good gut bacteria and relieves digestive distress, whereas calmness is brought on by the natural substances discussed above. 

Want to hear a pro tip from this Peptiva review? Combine the two products I mentioned here with some fiber for optimal benefits. Fiber serves as food for the gut bacteria and helps them flourish in your gut. This allows them to better compete with those bad bugs in our gut. 

If you do not consume sufficient fiber already, then I recommend you start slow. 

How to Take and Dosage

The instructions to take this are exactly the same as Peptiva + Sleep but you can probably take it more towards the end of the day, not necessarily right before bed. 

How much does it retail for? It costs $65 for a box of 30 capsules on their official website. 

Almost there. I have one more product to discuss with you which is slightly different. Keep reading this Peptiva review to find out what the brand’s final product can offer you.

Peptiva Vegetarian Digestive Enzymes + Prodigest Review

Peptiva Vegetarian Digestive Enzymes + Prodigest Review
Peptiva Vegetarian Digestive Enzymes + Prodigest

Now, this product is slightly different from the above two because it’s designed to help you better digest your food so that you don’t have issues like gas or bloating.

The reality is that if food is not properly broken down, it reaches the large intestine undigested which results in symptoms of gas, bloating, and abdominal pain. 

What helps us digest our food, you may ask? It is basically the proteins called enzymes that help us break down food so that we can harness all that vitamin and mineral goodness. Unfortunately, some of us don’t make enough digestive enzymes to digest the food. 

Remember the phrase “lactose intolerant”? All that means is that their body is not producing the enzyme lactase to digest the lactose sugar present in dairy.

Similarly, we have enzymes to digest proteins, carbohydrates, and fats in all food. Let’s take a look at how many of these enzymes are present in this product.

Ingredients Label 

There are 17 of these enzymes present in this blend per capsule which includes lactase and proteases to name a few.

Taking the digestive enzymes found in Peptiva Vegetarian Digestive Enzymes + Prodigest can probably save you from the embarrassment of excusing yourself in public because you just had a bowl of beans and can’t stop burping. 

This product also contains a patented formula called Prodigest which is a blend of artichoke leaves and ginger root. These names are likely familiar to you as they are commonly found in the grocery store. But you may not know that these extracts bring their own significant benefits which I will discuss below.

Nutritional Value

Apart from the extensive digestive enzyme blend, there is 320mg of ginger and artichoke present in total per capsule. None of these products mentioned above contribute to your daily caloric requirements.


The benefits of a digestive enzyme blend are pretty self-explanatory. They help you digest your food, especially after a heavy meal. It also helps with bloating and other digestive issues, as shown in this study.

Ginger for digestive relief like nausea and indigestion is something we have heard of from our ancestors. But artichoke is a new one for sure. This combination has been shown to relieve digestive distress symptoms like pain, nausea, and bloating.

How Does it Work

Enzymes are basically substances that help us break the food down so that it is easier to digest it. Once we have enzymes, our body knows what to do with them. As a result, our digestive issues can be resolved. 

Ginger and artichoke are basically an added benefit to soothe our already existing digestive issues.

How to Take and Dosage

Make sure you take one capsule of this product immediately before a heavy meal with water to help you digest your food better. Unfortunately, this product is not vegan or gluten-free. You can buy a 30-day supply for $35

If you are still wondering whether you can take this product, then I invite you to continue reading this Peptiva review. 

Who Is Peptiva For? 

Peptiva Review

If you are someone that has occasional digestive issues and gets uncomfortable after a meal and are looking for something to help you sleep or feel calmer, this product is for you.

If you can’t eat certain foods like beans or gassy veggies because of the after-effects, then give the Digestive Enzymes blend a try. 

The product is made for adults over 18 and is not meant for children. Remember that if you are pregnant, lactating, or have a serious medical condition, consult your doctor first. 

Peptiva Side Effects

Peptiva Review

I’m sure you are wondering if this product has any side effects. Although side effects are rare, no product is free of them. The most common side effect of probiotics is temporary digestive discomfort like gas or bloating for the first few weeks as the body is trying to settle in. It should eventually disappear.

Rare adverse effects of melatonin include agitation, palpitations, nightmares, mood swings, fatigue, and skin irritation. If you do experience any of these side effects, be comforted in knowing that they are known to resolve once you stop using it.

Peptiva + Sleep can cause drowsiness and it is not advisable to be driving, operating any machinery, or performing any task requiring alertness. Because of this, it should only be taken 30-60 minutes right before you go to sleep. 

If you are taking any other medications, consult your doctor. 

Peptiva Reviews: What Do Customers Think?

Peptiva Review

Now that you can conduct a presentation on this product, let’s see what the customers really think about these products. 

The first stop was their official website, where one consumer wrote: “It is a great supplement. I was trying to use anything in the last 3 years to improve my sleeping cycle and nothing ever worked. 

Since the first tablet I used I fell asleep like a baby. In the morning I felt like new, asking what’s happened. I was not having a bad mood, no dry eyes. I really greatly thank Peptiva.” 

Another consumer said: “No more sleepless nights. This product does just what it says it will! I haven’t slept this good in years. My stomach is doing much better. It is a win-win situation.” 

Let’s move on to Amazon where these products have the following ratings: 

  • Peptiva + Sleep: 4.1/5 stars following 2,469 ratings 
  • Peptiva Advanced Digestive Relief: 4.3/5 stars after 431 reviews
  • Peptiva Vegetarian Digestive Enzymes + Prodigest: 4.1/5 stars with 538 ratings
Peptiva Review

One 5-star reviewer said: “I was pleasantly surprised how much I like the Peptiva Probiotics + Sleep Support. In the past, I have taken an otc sleep aid and a separate probiotic which was costly. I had tried taking melatonin at night but found I was having very vivid nightmares so I discontinued using it.

The customer went on to say: “I have not had that issue with Peptiva and I am well-rested in the morning. I highly recommend this product for a great night’s sleep while gaining good gut health.”

Another consumer boasted that they, “really love this product. It helps with IBS! Won’t go any place without it!” 

On iHerb, one reviewer wrote: “This has been an amazing product for me. After a life of issues, this has been a turnaround for me. Added bonus is the fact that I have been sleeping better since taking this. I’ve been happier and feeling my best.”

Some buyers did complain that it was expensive, but remember that it can be considered a 2-in-1 product for its calming effects on sleep in addition to its digestive aid. 

Is Peptiva Worth It?

Peptiva Review

So here is the big question: should you buy this product? There is clinical evidence of the safety and efficacy of their ingredients which is also backed by 5-star customer reviews. So, why not just try it out and press that “add to cart” button? 

Needless to say, taking this product while maintaining a good healthy lifestyle with proper food and sleep hygiene is very important. There is no substitute for that, period! Still, thinking about it? Why not try their 15-day trial offer and see if it works for you! 

Peptiva Promotions & Discounts 

Peptiva Review

I tried and tried to find you a promotion or a discount but could not find one at the time of this Peptiva review, besides the 15-day free sample I mentioned. Keep your eyes open though because you never know.

Where to Buy Peptiva

Peptiva Review

You can purchase their products directly from their official website. You can also buy their products on Amazon and GNC. 


Peptiva Review

Is Peptiva vegan?  

The Peptiva + Sleep and Peptiva Digestive Advanced Digestive Relief are vegan but the Peptiva Vegetarian Digestive Enzyme + Prodigest is not. 

Is Peptiva gluten-free? 

The first two products are gluten-free but Peptiva Vegetarian Digestive Enzyme + Prodigest is not.

What is Peptiva’s Shipping Policy?

Peptiva shipping costs start at $5 and can go up depending on your location and the amount you order. It takes about 1-5 business days to receive the order via USPS. It does not look like they ship internationally but if you can, try to order the product on Amazon. 

What is Peptiva’s Return Policy?

They offer a 30-day money-back guarantee that includes a refund of the shipping charges. For the 15-day trial, you can cancel the order up to 18 days after your purchase. 

How to Contact Peptiva

If you have more questions beyond this Peptiva review, you can contact them using a few different methods:

  1. Email: [email protected]
  2. Call or Text: 1-800-355-6050
  3. Mailing Address – Canada: PO Box 1101, North York, Ontario M3J 0L2 Canada
  4. Mailing Address – the US: Peptiva, 2323 South 3600 West, West Valley City, UT 84119
  5. Fill out their online contact form.

Check out related reviews you might like:

Naturewise Probiotic Review

Skinny Fit Super Youth Review

Full Leaf Tea Company Review

Perfect Food Review

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