Isagenix Review

About Isagenix

Isagenix Review

With America’s rising obesity rate, losing weight is one of today’s biggest struggles. Understanding the vast market for weight loss, Isagenix manufactures products to become a leaner, healthier, energetic, and younger version of yourself. 

Amongst other awards, Isagenix holds the throne for being Arizona’s Most Admired Companies in 2021. Boasting an impressive Instagram following of about 150K, this Isagenix review is here to help you understand this company better. 

Is this multi-level marketing company genuinely worth the investment? Will their products help with your weight-loss goals? Stay tuned as I give you all the details about the company, its products, ratings, and whether investing in them is worth it or not.  

Overview of Isagenix

Isagenix Review

Founded by the couple Kathy and Jim Coover, Isagenix began in 2002. With its headquarters in Gilbert, Arizona, this husband-and-wife couple and their son, Erik, have managed to formulate innovative products catered to anyone looking to be healthier and a better version of themselves. 

Trademarking the “Art of Well-being,” Isagenix believes in interconnectedness and that people, science, and community co-exist.

Although their products have scientific studies[1] to prove their efficacy, this Isagenix review is not convinced as they are funded by the company.  

They also claim to be third-party tested, but there’s no seal of proof. Another point to note is that you can only buy their products through their website or independent associates, who have personal incentives to sell them.

Although I’ve got some qualms about these claims, their products cater to looking, feeling, eating, and moving for our health and longevity. 

The company’s goal is to have all packaging recycled, compostable, and reusable by 2028. Only time will tell whether Isagenix meets these goals. 

This was a short glimpse into the company, but this Isagenix review will soon hone in on three of its most popular products. Before that, let’s check out this brand’s highlights.  


  • Company offers opportunities to work as an independent associate
  • Products for weight loss, beauty, wellness, and detoxing 
  • Products use ethically and sustainably-sourced raw materials
  • Follows cGMP guidelines for product manufacturing
  • All products are gluten-free, except SlimCakes
  • Scientific studies have been done on some products to prove their efficacy
Isagenix Review

Isagenix Collagen Elixir Review

According to the Cambridge dictionary, an elixir is a “substance, usually a liquid, with a magical power to cure, improve, or preserve something.” Isagenix manufactures a Collagen Elixir to assist you with graceful aging. 

What I mean by that is that collagen can help maintain the skin’s elasticity and delay those unwanted wrinkles that are an inevitable part of aging. 

The Isagenix Collagen Elixir comes in individual servings and in 100% recyclable glass bottles to preserve their freshness. Unlike other collagen powders, this product is a premade liquid, making it easier to grab-n-go. 

When it comes to its cost, here is the breakdown: 

  • For Guests, each ten bottle pack costs $50 + shipping costs
  • For Preferred Customers, it costs $44  + shipping 
  • For Subscribed members, it also costs $44 with free shipping on the first order. 

When I look at this cost with a critical eye, each serving of collagen costs $5, which is quite expensive if you ask me. 

What are the other ingredients in this elixir? Where does the collagen come from? Stay tuned, this Isagenix review will highlight some key points about this magical drink. 

Ingredients Label

Claimed to give you a “glow inside out,” this dairy-free, processed sugar-free, gluten-free beverage is made from marine collagen peptides.

The collagen comes from different types of fish, and Isagenix claims this product has a Marine Stewardship Council certification signifying responsible fishing practices.  

Apart from collagen from wild-caught cod, haddock, and pollock, this elixir contains vitamin C, zinc, and biotin. Lastly, it contains a proprietary blend of herbs such as aloe vera, chamomile, acerola cherry, and goji berries, the latter two of which are great natural sources of vitamin C. 

Inactive ingredients include apple juice concentrate, acacia gum, sunflower lecithin, stevia extract, citric acid, and natural flavors to enhance the taste. 

Nutritional Value

Each two-ounce bottle contains 50 calories, out of which there are 7g of carbohydrates with 5g of sugars. There are also 5g of protein present along with 50mg of vitamin C, 30mcg of biotin, 3 mg of Zinc, and 30 mg of sodium. 

In terms of marine collagen, there is 5g in each bottle and 160mg of the proprietary blend. 


Research engines are flooded with articles on collagen and its benefits. Let’s take a look at some of them: 

Skin Health

Collagen is a protein omnipresent in our body that, unfortunately, declines[2] with age. A collagen supplement can strengthen the skin by improving its elasticity. Collagen also has a hydrating effect on the skin.

Several review articles[3] suggest that taking 3-10g of collagen for 2-3 months can have substantial benefits on skin elasticity. 

It’s important to mention that smoking, alcohol, and a diet rich in sugars can enhance the decline of collagen. So, a healthy diet with a collagen supplement is ideal. 

Joint, Bone, and Muscle Health

A review article[4] summarized the beneficial actions of hydrolyzed collagen by protecting the cartilage and bone as we age, reducing pain. 

A study done in 2018[5] on post-menopausal women noted an increase in bone mineral density when supplemented with 5g of collagen.

Other Benefits

Collagen may benefit heart health, gut health, and hair and nails, but more studies are needed in these areas.  

Let’s look at some of the other ingredients present in this blend. 

Biotin[6]: This vitamin plays an essential role in several processes in our body. It is important to note that the Food and Nutrition Board recommends 30 mg/day of biotin. This collagen elixir has 30mcg of biotin in each drink, so you have to obtain the rest from a diet rich in egg yolks, milk, nuts, etc. 

Vitamin C & Zinc: We all know the benefits of these nutrients for immunity, but what do they do for our skin? These nutrients work as antioxidants and help the body fight off harmful free radicals. These nutrients help with collagen synthesis[7] as well.  

Similarly, goji berries are rich in antioxidants and have anti-aging benefits as well. Aloe vera[8] has soothing, hydrating, and elasticity-maintaining properties for the skin.

How Does It Work

There are several types of collagen in our body, such as Type I, II, III, and IV, but Type I is found in marine collagen and is one of the most abundant[9] collagen types found in our body. 

Also, collagen in supplements is broken down into smaller segments called peptides, making them more absorbable[10].  

How to Take & Dosage 

I couldn’t find clear instructions on taking this product, but our educated guess is that you consume one bottle anytime during the day. There is no hassle of mixing a powder into a liquid since it’s already in a liquid form. 

Isagenix IsaLean Shake Review

Known for its 30-day weight loss program, Isagenix IsaLean Shake is one of the many products sold in Basic, Premium, Value, and Ultimate packs.

Isagenix calls it a “superfood meal,” which is quick, tasty, and easy to take. These shakes contain whey protein and 23 other vitamins and minerals and the brand claims that you can substitute these shakes for 2-3 meals a day. 

This Shake comes in several flavors, including Creamy Dutch Chocolate, Strawberry Cream, and French Vanilla. The powder is available in canisters or individual packs. 

When it comes to its cost, here is the breakdown: 

  • For Guests, one canister(14 servings) costs $57 + shipping costs
  • For Preferred Customers, it costs $49  + shipping 
  • For Subscribed members, it also costs $49 with free shipping on the first order.

Ingredients Label

This shake’s ingredient list is massive, so brace yourself as I try and simplify what’s in each bottle. 

The main ingredient is Myo-IsaLean Complex, which contains whey protein concentrate and milk protein. We get whey protein from milk. Isagenix claims to source theirs ethically from pasture-raised cows. There are 24g of protein in each serving of Isagenix IsaLean Shake

There are 23 vitamins and minerals such as Vitamin A, B1, B2, B5, B6, B7, B12, folic acid, D3, magnesium, and potassium.

These shakes also contain enzymes to help digest proteins, fats, and carbohydrates, such as lactase, cellulase, lipase, protease, amylase, bromelain, and papain. 

One sweetener in this shake is fructose, a type of sugar found in fruits. It is combined with a lot of fiber and is present in minute amounts in fruits. And then there is stevia which is a natural sweetener from plants.

Some scientists[11] speculate that overconsuming fructose can lead to metabolic disorders such as diabetes, obesity, and nonalcoholic fatty liver disease. If you have diabetes or are at risk for it, you don’t want to consume a lot of fructose in packaged products. 

There is also maltodextrin as another form of carbohydrates in this shake. It is a highly processed powder obtained from corn, wheat, rice, or potato starch.

Nutritional Value

Each serving contains 240 calories, 6g of fat, 24g of protein, and 24g of carbohydrates. There is also 10g of sugar in each serving. As a result, I do not recommend these shakes for diabetics!


Let’s hone in on the benefits of whey protein, since that’s the main ingredient in the Isagenix IsaLean Shake

Whey is a well-studied[12] protein that has proven to build lean muscle and help lose body fat. However, this study[12] shows that it is only effective when combined with resistance training, something Isagenix fails to mention.

Whey contains several essential amino acids that our body can’t produce, such as leucine and cysteine. Some other benefits of whey are:

  1. It is easily absorbed[13] into the blood.
  2. It helps in building muscle. 
  3. It promotes satiety[14] and fullness, which prevents snacking and consuming excess calories. 

However, it is essential to remember that this shake has added sugars. If you replace this shake with your regular meals, you will consume a lot of sugar, leading to other issues such as poor blood sugar balance. 

How Does It Work

As mentioned briefly in the benefits, whey protein increases satiety and builds muscle. This can help with our weight loss goals. However, when following a weight loss plan, it is essential to eat sufficient nutrients in our diet and resistance training.

Starving yourself or eating insufficient calories can lead to weight gain when you come off the diet. 

How to Take & Dosage 

Mix 2 leveled scoops in water or any beverage of your choice. Isagenix says you can have the Isagenix IsaLean Shake 2-3 times per day. 

Isagenix 9 Day Cleanse Review

The Isagenix 9 Day Cleanse system consists of the IsaLean Shake, Isagenix Snack Bites, Natural Accelerator, and Cleanse for Life. Each product is designed to support your cleanse, keep you full, and eventually help you lose weight. 

This Isagenix review would like to tell you that no laxatives are used in these products. Isagenix claims that some ingredients “boost metabolism” and “filter out toxins” using natural means. 

This 9-day system works because there are “Shake days” and “Cleanse days.” On Shake Days, you drink 2 shakes, 2 Natural Accelerator capsules, Isagenix Snack Bites, a 400-600 calorie meal for dinner, and lots of water. 

You drink the Cleanse for Life product, Isagenix Snack Bites, and Natural Accelerator product on cleanse days. 

When it comes to its cost, here is the breakdown: 

  • For Guests, the whole package costs $187 + shipping costs
  • For Preferred Customers, it costs $161 + shipping 
  • For Subscribed members, it also costs $161 with free shipping on the first order.

Let’s take a look at some of the main ingredients. 

Ingredients Label

The IsaLean Shake ingredients are those mentioned above. The gluten-free, non-GMO  Isagenix Snack Bites contain peanut butter, gluten-free oats, and fava beans. They are sweetened with erythritol, stevia, and monk fruit. 

There is also DNF-10 in the snack bites, which are broken down proteins obtained from yeast. This food additive has an anti-obesity effect, as per some studies[15]

The Natural Accelerator product contains heat-producing substances (thermogenics) to naturally boost metabolism, including green tea and cayenne. It also contains apple cider vinegar, cinnamon, chromium, and cocoa seeds to maintain healthy glucose metabolism after a meal. 

The Natural Accelerator is dairy-free, vegetarian, gluten-free, and soy-free. 

The Cleanse for Life product has liver-supporting ingredients mixed into a proprietary blend which includes turmeric, peppermint, aloe, bilberry, and licorice. 

It also contains niacin, B6, and B12 as vitamins. These herbs have antioxidant properties to protect against oxidation. 

The inactive ingredients of Cleanse for Life include fructose. 

Nutritional Value

The Isagenix snack bites contain 5g of protein, 4g of fiber, and 2g of sugar, totaling 100 Calories per serving. There are negligible calories in the Natural Accelerator product. 

In the Cleanse for Life product, each serving has 20 calories with 5g of carbohydrates, 4g of sugars, and 1000mg of a proprietary blend that includes several botanicals. 


One benefit of this 9-day cleanse is that it is not just a water fast, unlike other cleanses. You are still taking in some calories even though they are kept to a minimum. 

However, it is not a long-term fix for any problem. This is a temporary cleanse for 9 days, after which you go back to your routine. Chances are that you may gain the weight back. 

Now, let’s go over some Cleanse for Life benefits:

Betaine HCl: Some studies prove that this ingredient may help reduce body weight, but more research is needed.

B vitamins: There is some research[16] to show that sufficient levels of B12 are inversely related to obesity. However, this doesn’t translate to B vitamins helping you lose weight. More research is needed to understand these claims. 

Inositol: There are also some studies[17] that show Inositol can help progress weight loss, but more research is needed on this topic.

How Does It Work

As described previously, the substances and botanicals in these products may help you burn fat faster.

The cleanse days are like fasting days, where you press the reset button and consume minimal calories. Shake days allow you to have two shakes and a small meal, but you are still somewhat restricted. 

The action of restricting calories, ingesting sufficient protein to maintain satiety, and using supplements to potentially help you burn fat may eventually help you lose weight, temporarily.

How to Take & Dosage 

Take one scoop of powder dissolved in 2-4 ounces of water, 1-2 ounces of liquid, or one 2-ounce bottle of Cleanse for Life up to twice daily.

For the Natural Accelerator, take one capsule with water as written in the cleanse directions. 

On Shake days, you can consume up to 2 shakes per day. 

Who Is Isagenix For? 

Isagenix Review

These products are for any adult anyone looking to feel better, move better, or look better. Isagenix has a wide range of supplements to meet your demands

If you are pregnant, breastfeeding, or have a medical condition, please consult your physician. 

Isagenix Side Effects

Side effects of whey protein are mainly digestive upsets[18] like gas, bloating, diarrhea, and cramps. If you are allergic to cow protein or have lactose intolerance, the IsaLean Shake is not for you. 

The presence of biotin in the Collagen Elixir can interfere with test results[19] relating to the heart and thyroid. However, collagen is considered to be safe in general. 

According to some studies[15], DNF-10 is considered safe and non-toxic, even at high doses. 

Since several herbs are present in the Cleanse for Life product, it is best to talk to your doctor, especially if you have medical conditions and take pharmaceutical drugs. 

Also, please consult your physician if you are pregnant, breastfeeding, or have any other medical conditions. 

Isagenix Reviews: What Do Customers Think?

Isagenix Review

When it comes to Isagenix customer reviews, I checked their official website first. The Collagen Elixir product has a 4.9/5-star rating with 110 reviews. 

As I mentioned earlier in this Isagenix review, they are in the form of before and after pictures. The other two products reviewed above did not have any thoughts on their website. 

On Better Business Bureau, the company has an A+ rating of 2.8/5 stars. There are only ten customer reviews, most of which are positive. Let’s take a look at some of those comments. 

One happy customer said, “Isagenix is an amazing company with amazing products! I’ve been using the products for over three years now and can’t go a day without them. I’ve also been actively earning an income since my first week on the products. Amazing compensation plan all-around amazing company!” 

Another associate commented on its business model and said, “Amazing Products, Excellent Support & Leadership! Best that I’ve ever encountered in my over 12 years of earning an income from home. Better than the income, leadership & support is the results! Results Matter!” 

Another delighted user said, “I absolutely love the products & the company!!! Beyond excellent customer service and products that stand up to their claim. Life changing results. Healthy really does start on the inside” 

On Amazon, the Cleanse has 1,217 ratings with a 4.4/5-star rating. One consumer commented, 

“I used this product in 2008, and worked wonders. I gained weight a few years ago and had trouble losing the extra pounds until I purchased Isagenix 30-day weight loss program, and I have seen the difference. I love this product and will continue buying Isagenix.” 

Some negative reviews talk about the company’s poor customer service, but individual experiences can vary. Overall, the positive feedback outweighs the negative. 

Is Isagenix Legit?

Isagenix Review

Isagenix is based on an MLM (multi-level-marketing) model and claims its products help to  “increase metabolism” and “burn fat.” However, the scientific articles on their website are biased since Isagenix funds them. 

My research shows these claims are only partly true. They also claim to be third-party tested, but there is no certification proving that. 

Additionally, the company uses several proprietary blends, which do not allow consumers to know the exact amount of ingredients present. Lastly, some products have been recently recalled due to over-fortification of vitamins and minerals. 

Considering these facts, I conclude that Isagenix products are legit– to some extent. Consultation with a practitioner is highly recommended before trying these products. 

Is Isagenix Worth It?

Isagenix Review

Isagenix products may be safe and use quality ingredients with some scientific backing. They may be suitable for short-term weight loss but living off minimal calories and restricting your choices may only increase your cravings in the long run. 

In short, I believe there is no shortcut to weight loss. A healthy and balanced lifestyle with a whole-foods based diet is key to optimal health and energy levels. I’ll let you decide if Isagenix is worth it or not. 

Isagenix Promotions & Discounts 

Isagenix Review

Unfortunately, this Isagenix review couldn’t find any promotion or discount codes.

Where to Buy Isagenix

Isagenix Review

I encourage you to buy Isagenix products from their website or independent associates to assure authenticity. However, online companies like Amazon do carry the product. 


Isagenix Review

Is Isagenix vegan?  

None of Isagenix products are certified vegan.

Is Isagenix gluten-free? 

Yes, all products are gluten-free except the Isagenix SlimCakes.

What is Isagenix’s Shipping Policy?

Isagenix ships via FedEx in the United States and UPS within Canada.

  • For products less than $50, ground shipping costs $9
  • For products over $50, it costs $11 or 7% of the total (whichever is greater)
  • It takes 5 business days for US shipping and 7 for Canadian shipping

If you are in Arizona, you can pick up your order. There is also something called IsaDelivery, where you can get a year of unlimited ground shipping with no minimum purchases. 

What is Isagenix’s Return Policy?

If you are not satisfied with their products, you have 30 days to return them if they’re a first-time purchase. There is no refund on shipping costs, nor are there any exchanges.

To return a product, you can email [email protected] or call (877)- 877-8111. 

How to Contact Isagenix

If you’ve still got questions about Isagenix that I didn’t cover in this review, here are a few ways to get in contact with the brand to find out more:

  • Office Phone Number: 480 889 5747
  • Other phone numbers: 1 877 877 8111 (toll-free), or 480 889 5777
  • Fax number: 480.636.5386 
  • Hours of operation: Monday-Friday: 6 am – 6 pm, Saturday: 6 am – 2:30 pm, closed on Sunday
  • Customer support email: [email protected]

There is also a 24/7 virtual assistant you can chat with on their website. Or, you can go old-school and mail them at:


155 E. Rivulon Blvd.

Suite 104, Gilbert, AZ 85297

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Article Sources

  1. Cho, S., Gumpricht, E., & Despain, D. Isagenix Clinical Research Summary
  2. Quan T, Fisher GJ. Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review Gerontology. 2015;61(5):427-34
  3. Choi FD, Sung CT, Juhasz ML, Mesinkovsk NA. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications J Drugs Dermatol. 2019 Jan 1;18(1):9-16
  4. Porfírio, E., & Fanaro, G. B. Collagen supplementation as a complementary therapy for the prevention and treatment of osteoporosis and osteoarthritis: a systematic review Revista Brasileira de Geriatria e Gerontologia, 19, 153-164
  5. König, D., Oesser, S., Scharla, S., Zdzieblik, D., & Gollhofer, A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study Nutrients, 10(1), 97
  6. Lipner, S. R. Rethinking biotin therapy for hair, nail, and skin disorders Journal of the American Academy of Dermatology, 78(6), 1236-1238
  7. Laudermilk, M. J., Manore, M. M., Thomson, C. A., Houtkooper, L. B., Farr, J. N., & Going, S. B. Vitamin C and Zinc Intakes are Related to Bone Macroarchitectural Structure and Strength in Prepubescent Girls Springer Link Calcified tissue international, 91(6), 430-439
  8. Kaminaka, C., Yamamoto, Y., Sakata, M., Hamamoto, C., Misawa, E., Nabeshima, K., Saito, M., Tanaka, M., Abe, F., & Jinnin, M. Effects of low‐dose Aloe sterol supplementation on skin moisture, collagen score and objective or subjective symptoms: 12‐week, double‐blind, randomized controlled trial The Journal of dermatology, 47(9), 998–1006
  9. Silva, T. H., Moreira-Silva, J., Marques, A. L., Domingues, A., Bayon, Y., & Reis, R. L. Marine Origin Collagens and Its Potential Applications Marine drugs, 12(12), 5881–5901.
  10. De Luca, C., Mikhal'chik, E. V., Suprun, M. V., Papacharalambous, M., Truhanov, A. I., & Korkina, L. G. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study Oxidative medicine and cellular longevity, 2016, 4389410
  11. Ter Horst KW, Serlie MJ. Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease Nutrients. 2017 Sep 6;9(9):981
  12. Hulmi JJ, Lockwood CM, Stout JR. Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein Nutr Metab (Lond). 2010 Jun 17;7:51
  13. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrère B. Slow and fast dietary proteins differently modulate postprandial protein accretion Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14930-5
  14. Paddon-Jones D, Westman E, Mattes RD, Wolfe RR, Astrup A, Westerterp-Plantenga M Protein, weight management, and satiety Am J Clin Nutr. 2008 May;87(5):1558S-1561S
  15. Ahn, Y., Kim, S., Suh, H. J., & Jung, E. Y. Toxicity Evaluation by Single and Repeated Administration of Yeast Hydrolysate DNF-10 Preventive nutrition and food science, 26(1), 75–81
  16. Sun Y, Sun M, Liu B, Du Y, Rong S, Xu G, Snetselaar LG, Bao W. Inverse Association Between Serum Vitamin B12 Concentration and Obesity Among Adults in the United States Front Endocrinol (Lausanne). 2019 Jun 27;10:414
  17. Donne, M. L., Et al. Effects of three treatment modalities (diet, myoinositol or myoinositol associated with D-chiro-inositol) on clinical and body composition outcomes in women with polycystic ovary syndrome Eur Rev Med Pharmacol Sci . 2019 Mar;23(5):2293-2301
  18. Parker, A. M., & Watson, R. R. Lactose Intolerance Science Direct Nutrients in Dairy and their Implications on Health and Disease (pp. 205-211). Academic Press
  19. Chun, K. Y. Biotin Interference in Diagnostic Tests Clinical Chemistry, 63(2), 619-620

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