Plenity Weight Loss Review

About Plenity

Plenity Weight Loss Review

When it comes to losing weight, you tend to restrict the foods you love and exercise as much as possible. Turning your head away from unhealthy foods, trying to stop yourself from eating that chocolate bar that’s calling your name—there’s a lot of temptation out there and you need the willpower to prevent yourself from spiraling into a major binge.

With the right support and tools, weight loss can become both manageable and attainable within a realistic amount of time. According to this review1, the degree of weight loss and how it’s maintained should not be the only measure of treatment success.

Physicians should support and encourage patients to make sustainable improvements in their diet quality and physical activities. Long-term lifestyle changes will also help to improve the health of patients even if they are unsuccessful in the pursuit of major weight loss.

Plenity might just be the answer to all your weight loss problems. The US-based company is an FDA-approved tool to help you lose weight, even when you’re eating all your favorite foods!

The positive reviews and media for the brand has shown up in outlets such as Forbes, Healthline, and TechCrunch, and with its growing online presence—4k followers on Instagram; 8k likes on Facebook—it’s not surprising to see this brand grow in popularity! 

We made sure to trim the fat for you in our Plenity weight loss review, so you can browse through the company’s policies, pros and cons, product reviews, customer reviews, and any FAQs before you decide whether the brand is one you’d like to take for your body’s journey. 

Overview of Plenity

Plenity Weight Loss Review

Owned by a private biotech organization, Gelesis was founded in 2006 by the current CEO, Yishai Zolar. The company created Plenity as an answer to the growing, or expanding, weight problem the US is experiencing. 

Though not available in pharmacies, Plenity can only be provided to those who qualify via an online conference through the brand’s site. If you are hoping your doctor will be able to prescribe it for you, that will happen. 

At the time of writing this Plenity weight loss review, your physician might be able to prescribe it as the company was expecting to start doing so in 2021. 

As with any new weight loss tool, there are some prime features that come with it. In order to make sure you have all the information you need, let’s take a look at some of them:


  • FDA-approved
  • No stimulants 
  • Prescription only 
  • Unique approach to weight loss supplementation
  • Majority of people lost between 5-10% of body mass 
  • Approved for adults 18 and older 
  • Wheat- and gluten-free 
  • Community of other Plenity members to discuss progress and have extra support 
  • Access to registered dietitians and experts in the medical field for advice as a Plenity member

Not that you have an overall idea of the good and bad parts of the brand, this Plenity weight loss review will go deeper into how this FDA-approved tool might be able to help you. 

Plenity Review 

Plenity Weight Loss Review

For anyone struggling to lose weight, hearing about Plenity might seem like it’s the Holy Grail. It isn’t like your typical weight loss pill that is full of stimulants or worse, a drug combination that will have long term effects on your body. What you need to remember is that Plenity is not a drug—it is seen as an instrument your body uses. 

What do we mean by that? Well, this Plenity weight loss review found that the brand is not considered a drug because it won’t be absorbed into your body, as many other prescribed pills might. It appears to work like a device that tricks your body into thinking it is already satiated[5] to prevent you from eating more.

Sounds too good to be true, right? Apparently, it isn’t! The components in Plenity grow to about 100 times their original mass. This way, your stomach and intestines, two important organs involved in knowing your limit, will think you have had enough food and signal your brain. 

But how does Plenity signal to your body that it is actually more full than it is? The key is in the components of the device—each pill contains thousands of superabsorbent hydrogel molecules2 that are made from citric acid and cellulose. In your stomach, these particles help keep you from overeating.

Plenity comes in a pack of three pills, which you are required to take with two glasses of water about 20-30 minutes prior to eating your meals, such as lunch and dinner. The company states that it will take about four weeks before you see any results. 

The brand also connects people with other Plenity members in their community as well as experts in the medical field and registered dietitians. To obtain the Plenity login, once you are prescribed the regimen from your doctor, you can log in and chat with other people who are also on the same weight loss journey as you. 

Of course, with any weight loss program, you have to be aware of other factors other than reducing your food intake. There are other things to consider when tackling your body mass—your genes, exercise level, way of life, and overall mindset will all play into whether you will see a huge difference.

If you believe that Plenity will help you reach a designated weight in order to be happy, then unfortunately, this program may not work for you. In order to fully embrace a new you, a lot of things need to change. The brand is merely the tool to help you get to your goal but this Plenity weight loss review believes it is not a magic dose that will change your body overnight.   

Who is Plenity for? 

Plenity Weight Loss Review

In order to receive a prescription for Plenity, you have to meet certain requirements. If you are aged 18 and older with excess weight or are obese with a body mass index (BMI) of 25-40 kg, then you may qualify however, that will be also be at the discretion of your family doctor.

This Plenity weight loss review finds if you are pregnant or are allergic to any of the key components in the pill, it is advised you should not take it. As always with any sort of major change to your body, check with your doctor before you even consider starting a weight loss journey. 

Comparison: Plenity vs. Noom 

Plenity Weight Loss Review

With all the information you have just received on the brand, it’s time for this Plenity weight loss review to compare the company to one of their competitors: Noom. 

Founded in 2008 by Saeju Jeong and Artem Petakov, Noom is a subscription-based digital weight loss tool and space that encourages people to build new habits in their weight loss journey. The two founders were focused on providing actual health care, doing their best to change the mindset towards how people approach their chronic diseases. 

Headquartered in New York, the company has made great strides in helping millions of people change their behavioral patterns so they can see long-term results. And after doing years of research, experimenting, and understanding what it takes to lose weight for good, Noom is now focusing on people with curable issues.  

The brand’s app can be used on your smartphone or tablet to help you journal and keep track of your daily progress. It also provides you with one-on-one coaching to help you get through those hard times.  

Although both companies are in the same weight loss industry, comparing the two brands is difficult because they are built on different concepts. Noom is an application that provides you with information and tracks various things for you, while Plenity is a supplement that you must take with meals. That being said, we can still compare prices and customer reviews.

Noom offers a free one-week trial, after which a subscription costs approximately $59/month if you sign up for their auto-renewal method. Each plan is totally unique and can be customized to each person, based on their health needs and goals. The brand also offers bundle pricing, i.e. a 4-month cost would be $139, which would save you quite a bit of money. 

As mentioned previously in this Plenity weight loss review, Noom is more concerned with changing people’s long-term habits. In this sense, they encourage people to adjust their way of living in order to have a more chronic disease-free life. 

In terms of reviews, many of the brand’s customers are happy with their results, having lost weight and changed their mindset in how they were approaching their health. However, many of the complaints stem from the technical glitches people experienced as well as the lack of customer service. 

Overall, as with any weight loss journey, Noom leaves the control in the user’s hands, which means you need to show up for yourself. The majority of people who committed to the brand’s process found it to be very helpful. 

If you want to learn more about Noom, check out our full Noom Diet Plan Review.

How Much Is Plenity?

Plenity Weight Loss Review

The Plenity cost amounts to $98 for a month’s supply, or about $2 per meal. Once you are subscribed to their program, your pills will arrive each month on an auto-renew plan. 

Plenity Reviews: What Do Customers Think?

Plenity Weight Loss Review

Since this Plenity weight loss review has taken you through the ins and outs of the brand, along with comparing it to a competitor, let’s get to the real meat of what customers really think. 

Plenity has many customer testimonials on their website but because the brand was recently approved by the FDA, it hasn’t shown up on sites like Trustpilot. However, certain media outlets like Wellness Verge, Cooking Light, and Illuminate Labs have taken the time to review the pills and what results they were able to achieve. 

Wellness Verge gave the product an expert rating of 4.3/5 stars in its 2021 Plenity Review article. Writer Melissa Mitri, MS, RD, concludes, “Plenity is a weight loss aid that could serve as a supplement to a healthy diet and lifestyle plan…Given its good safety profile, it may be a helpful option if one is looking for a non-invasive way to lose weight.”

In 2019, Cooking Light chatted with Violeta Popov, MD, PHD, FACG, to get her expert opinion of Plenity. She believes “…Plenity could be an excellent part of a long-term plan for those with BMIs of 25 or higher…this could be a beneficial intermediary before having to resort to an invasive medical procedure or a drug with frightening potential side effects.”

An updated 2021 Plenity Review in Consumer Health Digest claims, “Looking at the official website, almost every Plenity review raved about the great weight loss benefits of this product. Many users said it made their journey that much easier and that they never felt hungry. There were few poor reviews on the official site, if any at all.” 

Overall, Plenity feedback in the media is highly positive.

Is Plenity Worth It?

Plenity Weight Loss Review

For anyone who is looking for a springboard to their weight loss, Plenity is worth trying. With its FDA-approval and customer testimonials, it seems the brand has been given the green light for the growing obesity issue in the States. 

The important part to remember about taking Plenity is that it must be taken before lunch and dinner, with two glasses of water. It cannot be taken on its own as the water activates it and helps you to feel full. If you take it without following the instructions closely, it may not be as effective. 

However, given the high price point, this Plenity weight loss review feels the product is geared more towards people who have the disposable income to spend on a monthly regimen like this. 

Plenity Promotions & Discounts 

Plenity Weight Loss Review

At the time that this Plenity weight loss review is written, there are no notable promotions or discounts featured on the brand’s website. 

Sign Up For Plenity

Plenity Weight Loss Review

To see if you qualify for Plenity, visit the brand website at myplenity.com, then click the ‘Get Plenity Now’ button. A medical professional will speak to you about your health history to ensure if you are the right candidate for the brand. 

Once you are cleared for the weight loss tool, your Plenity supply will be shipped to you via 2-day delivery.  


Plenity Weight Loss Review

Is Plenity FDA approved?

Yes, Plenity is FDA-approved. It received its approval in 2019 after it was able to show its potential in their 2018 study. In the double-blind and placebo controlled study, they showed 436 adults who fit the Plenity body mass index profile to take the tool or a placebo for six months. Those who received the weight loss aid lost more weight than others who didn’t. 

The study also did not highlight any major safety concerns about the weight loss tool. However, it only followed the patients for a short period of time under a controlled environment, so there may be long-term effects that remain to be seen. Nonetheless, the FDA deemed it safe for consumers. 

What drug is Plenity?

In comparison to other weight loss pills on the market, Plenity does not fall under the drug category. The weight loss tool is not considered a drug because it isn’t absorbed into your body at all; it is a non-addicting aid to signal to your body that it is full.  

What are the side effects of Plenity?

Based on the clinical study Plenity performed, the most common side effects were feeling too full, some bloating, excessive gas, stomach pain, constipation, diarrhea, and even some possible weight gain. 

Of course, please bear in mind that everyone has different body compositions and will react to weight loss aids in a variety of ways. This Plenity weight loss review recommends always consulting your doctor prior to starting any sort of weight loss program.

How do I cancel my Plenity subscription?

If you are unhappy with your Plenity subscription, want to adjust the frequency, or want to cancel your auto-refills, you will need to do the following:

  1. Log into your Plenity account.
  2. Click on the Treatments tab.
  3. Choose the specific card you want to manage (if you have multiple).
  4. Once it expands, head down to ‘Have too much supply?’. 
  5. Choose the Manage Plan button.
  6. Decide the amount of time you would like to delay the next shipment or to turn off auto-refills entirely.  
  7. You will receive a confirmation that auto-refills has been turned off. 

If you are still unable to turn off your auto-refills, then you can contact the Ro Care Team through the following methods:

What is Plenity’s Shipping Policy?

If you qualify and receive a prescription from Plenity’s medical professional or your own doctor, you can go on the brand’s website and order your supply. Once you place the order, it will be shipped to you via a free 2-day delivery. 

This Plenity weight loss review would like to note that the brand is only available for all US states, with the exception of Virginia.  

What is Plenity’s Return Policy?

Prescription products are not eligible for return or resale. If you feel like the company has made a mistake filling out your prescription or you have received a damaged or incorrect shipment, contact the account, billing, and shipping reps. 

How to Contact Plenity

The brand offers the following methods of contact:

For any account, billing, or shipping Information: 

The account, billing, and shipping Ro Care Team is only available from Monday to Friday from 9:30 am to 9 pm EST.


1.Hall, K.D. and Kahan, S. (2018). Maintenance of Lost Weight and Long-Term Management of Obesity. Medical Clinics of North America, [online] 102(1), pp.183–197. doi:10.1016/j.mcna.2017.08.012.

2.Madaghiele, M., Demitri, C., Surano, I., Silvestri, A., Vitale, M., Panteca, E., Zohar, Y., Rescigno, M. and Sannino, A. (2021). Biomimetic cellulose-based superabsorbent hydrogels for treating obesity. Scientific Reports, 11(1). doi:10.1038/s41598-021-00884-5.

Looking for more ways to stay healthy? Check out these great options below:

Factor 75

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Article Sources

[1] Appelhans, B. M., French, S. A., Pagoto, S. L., & Sherwood, N. E. Managing temptation in obesity treatment: a neurobehavioral model of intervention strategies U.S. National Library of Medicine Appetite, 96, 268–279
[2] Hall, K. D., & Kahan, S. Maintenance of lost weight and long-term management of obesity U.S. National Library of Medicine The Medical clinics of North America, 102(1), 183–197
[3] Egras, A. M., Hamilton, W. R., Lenz, T. L., & Monaghan, M. S. An Evidence-Based Review of Fat Modifying Supplemental Weight Loss Products U.S. National Library of Medicine Journal of obesity, 2011, 297315
[4] Crustolo, A. M., Ackerman, S., Kates, N., & Schamehorn, S. Integrating nutrition services into primary care U.S. National Library of Medicine Experience in Hamilton, Ont. Canadian family physician Medecin de famille canadien, 51(12), 1647–1653
[5] Nelson J. B. Mindful Eating: The Art of Presence While You Eat U.S. National Library of Medicine Diabetes spectrum : a publication of the American Diabetes Association, 30(3), 171–174
[6] Sannino, A., Demitri, C., & Madaghiele, M. Biodegradable Cellulose-based Hydrogels: Design and Applications MDPI Open Access Journals Materials, 2(2), 353–373
[7] Abdel-Salam, O. M., Youness, E. R., Mohammed, N. A., Morsy, S. M., Omara, E. A., & Sleem, A. A. Citric Acid Effects on Brain and Liver Oxidative Stress in Lipopolysaccharide-Treated Mice U.S. National Library of Medicine Journal of medicinal food, 17(5), 588–598
[8] Berthold, H. K., Unverdorben, S., Degenhardt, R., Unverdorben, M., & Gouni-Berthold, I. Effect of a Cellulose-containing Weight-loss Supplement on Gastric Emptying and Sensory Functions Wiley Online Library Obesity, 16(10), 2272–2280
[9] Nuttall F. Q. Body Mass Index: Obesity, BMI, and Health: A Critical Review U.S. National Library of Medicine Nutrition today, 50(3), 117–128
[10] Lentjes M. The balance between food and dietary supplements in the general population U.S. National Library of Medicine The Proceedings of the Nutrition Society, 78(1), 97–109

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