Nature M.D. Review

About Nature M.D.

NatureM.D. Review

Nature M.D. uses effective ingredients found in ancient medicine to totally transform your wellness from the inside out. Zeroing in on gut health, digestion, and nutrient deficiencies, the brand’s supplements nourish, soothe, and heal intestinal-related issues.

With a following of 31k on Instagram, it appears that many are on the search for better gut health[1]. The brand’s founder, Dr. Vincent Pedre, has been featured by the Martha Stewart Show and Good Morning America, among others, for his research on digestion.

Looking for something to ease gut pain, benefit digestion, or increase vitality? You may have found just the thing to do it. Before you buy, read through this NatureM.D. review.

We’ll fill you in on information about the brand and its product lineup, customer feedback, answer important FAQs, and more, to help you buy with confidence.

Overview of Nature M.D.

NatureM.D. Review

We’re at a critical part of existence. Rounding the corner of putting junk into our bodies into focusing on feeding them with meaningful ingredients that actually make us feel good.

But, poor digestion doesn’t always result from a poor diet[2]. It’s sometimes hereditary, caused by stress, or a lack of a certain nutrient. Whatever the cause, NatureM.D. wants to fix it.

The brand was founded in 2014 by Dr. Vincent Pedre, a gut health specialist and Cornell University grad.

Proud of every last ingredient that goes into its formulas, NatureM.D. carefully selects them from bountiful sources in places like Costa Rica, New Zealand, and India. The plants, herbs, and extracts they utilize are part of ancient remedies, “some of which have been used medicinally for more than 6,000 years.

Ancient medicine has been passed down from generation to generation with its benefits highlighted with visible improvements before accessing other pharmaceuticals. Harnessing these benefits and pairing them in a way to naturally heal and promote health is a great addition to whatever health plan that each individual has in place.

According to this review[3], thousands of years of experimentation were done to arrive at the conclusions that resulted in the conclusive medical practices being formed. While modern technologies and methods can be used to arrive at a conclusion, they can also be assessed accurately and more objectively using methods developed prior to modernization.

Located in Atlanta, Nature M.D. strives for sustainability, choosing to work with growers who have strong environmental practices in place.

NatureM.D. Review

Before we get into its restorative supplements, this NatureM.D. review will give you a quick rundown of the brand’s highlights.


  • Five unique formulas that focus on gut health, digestion, and nutrient deficiencies
  • Uses natural ingredients used for centuries in ancient medicine
  • Dedicated team has a combined knowledge of 75 years in gut health
  • Customers believe its products are effective
  • Bundle & save
  • Subscribe & save
  • Free shipping always
  • 60-Day Money-Back Guarantee
NatureM.D. Review

In a toxic world, natural health is vital[4]. The vitality-boosting brand offers five unique formulas to bring about better health by way of healing your gut, nourishing your cells, and improving digestion.

In the next section of this NatureM.D. review, we’ll go over what those five products are, their key ingredients, and what each one can do to enhance your overall wellness.

Nature M.D. Review

The digestive system is responsible for more than we know. Without proper digestion, we can say goodbye to energy, detoxification, and nourishment.

NatureM.D. developed 5 key products to help us flourish by healing, feeding, and protecting our digestive system with powerful, natural ingredients. Shoppers can bundle their orders into packs of three or six to save up to 25%.

We’ll get into the brand’s most popular product first, GutConnect 365.

NatureM.D. GutConnect 365 Review

An unbalanced gut can lead to depression, weight gain, and even disease, not to mention Leaky Gut Syndrome, a painful and dangerous disorder.

It’s important to keep our tummies in tip-top shape, and thankfully, we can do this naturally. The NatureM.D. GutConnect 365 is a tasty, vegan powder supplement that uses a heaping dose of L-Glutamine (5,000 mg) to heal and nourish your intestines.

L-glutamine is the most abundant amino acid in the body and the rate of consumption of this amino acid by immune cells is similar to that of glucose. According to this review[5], studies have determined that glutamine is an essential nutrient for lymphocyte proliferation and secretory activities, along with bacterial killing.

Other power-playing ingredients include organic slippery elm, marshmallow root[6], and aloe vera to combat the reasons why Leaky Gut happens in the first place. Available in vanilla cinnamon and chocolate coconut flavors, mix a scoop into your morning smoothie to start the day off right.

According to this study[7], the digestive benefits of organic slippery elm suggest that it has significant prebiotic potential due to its ability to modulate the gut microbiota by improving epithelium function by reducing inflammation and protecting from infection. 

You can enjoy a 10 oz tub (30 servings) of GutConnect 365 for $54.

NatureM.D. Synbiotic 365 Review

You may have tried probiotics before but didn’t feel like they were doing anything to help your IBS, excess gas, or extra weight. That may be because the strain wasn’t the right type for your body.

The NatureM.D. Synbiotic 365 uses a unique, albeit obscure, source of probiotics tested to be quite effective in assisting weight loss and improving digestive processes. This probiotic is called Lactobacillus gasseri BNR17, and it’s made from human breast milk. It’s also certified by South Korea’s food regulatory authority. 

According to this study[8], results confirmed probiotic properties when directly examining relief of IBS symptoms. While this study was a preliminary trial, it’s also important to be aware that only IBS symptoms were measured. 

This source may be the missing key to relief for many across the globe, but there are another 13 strains of probiotics packed into these delayed-response gel caps to assist in the job. Along with probiotics, this supplement contains prebiotics as well as vitamin B complex to relieve mental sluggishness and feed the probiotics what they need to thrive.

A total of 20 billion CFU, this shelf-stable, health-boosting supplement is $45. Each bottle contains 30 capsules.

NatureM.D. Enzyme 365 Review

Did you know that pineapples contain a natural digestive enzyme called Bromelain? If you suffer from poor digestion, especially after consuming fibrous veggies or fatty foods, rather than down an entire pineapple you can pop a NatureM.D. Enzyme 365

This review[9] shows some studies that demonstrate various fibrinolytic and anti-inflammatory activities which are considerably absorbable in the body without producing any major side effects. Bromelain accounts for many therapeutic benefits and also relieves diarrhea and cardiovascular disorders.

One bottle contains 60 delayed-release gel capsules, meaning they’ll get to work in the proper place and won’t get broken down by stomach acids. Poor digestion can lead to low energy after a meal if you find your body doesn’t properly digest certain foods or you have a ton of excess gas that you’d rather not.

The NatureM.D. Enzyme 365 capsules are available for $45.

NatureM.D. RevBiotics Review

You are what you eat. But if you’re not properly absorbing nutrients, does that statement still hold true? RevBiotics ensures that it’s true by assisting in digestion and leveling up your immune system.

The power-packed gel cap is able to do this thanks to Actazin Kiwi Fruit Powder[10]. Containing a high dose of vitamins, enzymes, and antioxidants, the little, but mighty, fruit supercharges your system to increase energy and improve your mood.

When looking at this study, the consumption of Actazin increased stool frequency which was measured by the Bristol stool score and measures of gastrointestinal comfort. There was an increase in bowel movement per week in the symptomatic population which concludes that it is considered a clinically meaningful effect.

One 30 capsule pack of the NatureM.D. 365 probiotic formula is $45.

NatureM.D. NutriProtein Review

Protein shakes aren’t new to the health and fitness game, but their formulas are certainly evolving. What used to be dairy-based-only shakes has transformed into a spectrum of every protein source and flavor you can imagine.

If you have digestive issues, chances are you’ve been told to avoid dairy, which is why the NatureM.D. NutriProtein is a good pick. It’s made with chickpeas, but before you turn your nose up at the friendly, little bean, understand that when in powder form, they make for a smooth base for a creamy shake. Plus, they contain a ton of fiber and nutrients!

With 15 servings per 19 oz tub, this vegan, soy-free, and gluten-free powder is filling, can increase energy, and assist in digestive help thanks to probiotics. In a chocolate-vanilla flavor, one tub of the NatureM.D. NutriProtein Powder is $54.

Who Is Nature M.D. For?

NatureM.D. Review

NatureM.D is for anyone struggling with digestive-related health issues. Its products are packed with gut-healing ingredients and geared towards repairing and preventing tummy troubles.

Certain products are specifically designed for those with Leaky Gut Syndrome, while others are more broad, like Synbiotic 365 and Enzyme 365, which many may find useful to increase energy and improve overall health.

Comparison: NatureM.D. vs. MaryRuth Organics

NatureM.D. Review

The world of natural medicine is expanding and people are learning that they can solve their ailments by simply introducing a certain compound or element into their diets or morning routines.

As the need for natural solutions to problems that previously required an Rx increases, so does the number of brands who say they have just the thing to heal you.

We’re going to be looking at MaryRuth Organics, a natural health brand that makes products that cover all areas of wellness, such as immunity, digestion, energy, and sleep. It also has children and pet-specific supplements that cover those same areas but in smaller or varying doses.

MaryRuth Organics has a wide spectrum of products, whereas NatureM.D. has just five. We’ll take a closer peek at one of each of the brand’s similar products to see if there’s anything that makes each of them the clear winner.

NatureM.D. Review

Staying with the digestive theme, we chose to put the MaryRuth Organics Liquid Probiotics against the NatureM.D. Synbiotic 356.

Our competitor’s product is, you guessed it, in liquid form. It has 12 probiotic strains and 40 servings but doesn’t state how many CFU it has. Unflavored, you can mix it with another liquid or take it as a shot. The Liquid Probiotics are $45.

Our featured brand’s probiotics are in capsule form and include 14 strains, including one special form. Each bottle has 30 servings and boasts 20 billion CFU. Symbiotic 365 is $45.

MaryRuth Organics is certainly less expensive per serving, but it uses fewer strains. NatureM.D. ‘s product also contains prebiotics and vitamin B complex. Our featured brand’s option may cost more, but it has all you need within it to get the most out of your probiotic.

Is there a clear winner? We think so, but everyone’s preferences differ. MaryRuth Organics is an excellent brand that makes a wide range of wellness products. If you’re looking for a brand that’s more specifically catered to improving gut health, NatureM.D. could be your best bet.

NatureM.D. Reviews: What Do Customers Think?

NatureM.D. Review

Potent ingredients? Check. Thorough information? Check. Promising effects? Check. But all of those criteria are all for naught if the brand’s products don’t work.

Customer feedback has become one of the most critical tools for online shopping and is the reason that this section of our NatureM.D. review exists. Below, you’ll read about real user testimonials from a variety of sites across the web. So sit tight, we’re about to find out if the brand’s products really work.

The key to any successful business is great customer service, so we headed to the Better Business Bureau to see what kind of score it gave our featured brand. Delighted to find an A+ rating and almost 4/5 stars from 123 shoppers, we learned that over the last three years the brand had just 23 customer complaints and has resolved all of them.

Happy buyers write of improved digestion, sleep, and even fewer yeast infections. Of the difference the brand’s supplements make, one NatureM.D. review said, “I missed 4 days in a row and my bloating came back uncomfortable gut feeling, and non-regularity.” That’s usually a good sign something is working in your favor.

NatureM.D. Review

What about the bad? Reviews consist of things like poor customer service, long shipping times, and issues with orders. There’s nothing out of the ordinary that stands out as common or alarming.

Feeling like the brand has a solid customer service team, we turned to the Wellness Verge, a health blog, to see how they scored NatureM.D. and its Gut Connect 365. Finding a 2.4/5 star rating, we soon learned that the review found no evidence to support the claims made by the brand.

Here’s a rundown of how they came to that conclusion:

  • Protects and supports healthy gut lining: Moderate evidence
  • Improves digestion: Limited evidence
  • Beats bloat: Limited evidence
  • Improves mood: No evidence
  • Boosts energy: No evidence
  • Supports weight loss: No evidence
  • Improves sleep quality: No evidence
NatureM.D. Review

The NatureM.D. review said that while there isn’t a ton of evidence to back the brand’s claims, there is some that suggest this product can help with intestinal issues. It’s also important to note that there is often a lack of scientific evidence when it comes to natural ingredients, yet these ingredients have been used for centuries in ancient medicine, like Slippery Elm Bark.

When it comes to feedback, it depends on which source you read. Some people have great success with a product while others don’t. Certain articles are positive and others are negative. In fact, finding an unbiased review is rare, of course, except here.

To balance things out, we checked out the wellness blog Fit Trim Happy who conducted a review on Synbiotic 365. Contrasting the last source we used, this one explains how useful each one of the ingredients in the formula is and explains why.

NatureM.D. Review

After conducting their own research, the review concluded that the product is “effective,” and thanks to “generous use of natural probiotics that are often already found in your body,” its effectiveness is due to the fact that “it was designed for your body to easily accept it and put it right to work!

That’s an interesting point, as the body is able to identify and use elements more easily when they already know what they are.

Finding customer feedback for NatureM.D. was an interesting journey. There will always be people who respond better to any type of product, especially supplements. Are the brand’s products effective? From what we’ve read, we think so.

 Is NatureM.D. Worth It?

NatureM.D. Review

Getting our digestive tract in order is critical to a healthy, energetic life that doesn’t involve constant trips to the bathroom. NatureM.D. products help to bring about balance, tailoring them to five different needs that all revolve around proper digestion.

From feedback, we’ve learned that the brand’s digestive-assisting powders and capsules indeed work, even if technically, there isn’t a ton of evidence to back that up.

Its products are expensive, no doubt, but so are regular visits to the hospital or clinic, along with synthetic prescriptions. Of course, before you start any new supplement, it’s good to consult your doctor, but after you’re given the nod of approval, relief may be a few scoops away.

This NatureM.D review must note that there is a California Prop 65 Warning for all of the brand’s products. This means that they can expose you to certain chemicals that the state of California has stated can cause cancer and birth defects. The brand does not state exactly what that ingredient is, but all of them contain it.

NatureM.D. Promotions & Discounts 

NatureM.D. Review

Throughout this NatureM.D. review, we searched high and low on the brand’s website for deals. Here’s what we uncovered:

  • Free shipping
  • Subscribe and save 15%
  • Bundle to save up to 25%

Where To Buy NatureM.D.

NatureM.D. Review

The only place to buy the brand’s products is right from NatureMD.com.


NatureM.D. Review

Where is NatureM.D. made?

Every NatureM.D. supplement is made in the USA in GMP-certified labs.

Is NatureM.D. vegan and cruelty-free?

Only some of the brand’s products are vegan—NutriProtein and GutConnect 365. The brand does not state whether or not it tests its supplements on animals.

What is NatureM.D.’s Shipping Policy?

NatureM.D ships to many countries around the world. We’ll list those locations below, along with how long your order would take to reach you.

  • USA 2-6 business days
  • Canada 7-10 business days
  • Europe 7-10 business days
  • UK 7-10 business days
  • Australia & NZ 10-14 business days

What is NatureM.D.’s Return Policy?

You can try out NatureM.D. for 60 days, and if within that time frame you find it’s not doing the trick, send it back for a full refund (minus about $5 for restocking). The returns process goes something like this:

  1. To start a return, head to the Returns page and enter your order number
  2. If you’ve lost track of your order number, give the company a call or email using the methods listed in the next section of this NatureM.D. review
  3. Once your request is in, the company will send you a prepaid shipping label
  4. Print that label and stick it to the outside of your return box
  5. Drop it off at your local post office

How to Contact NatureM.D.

We hope that you found all of the information you came looking for and more in this NatureM.D. review. If you still have questions, use one of the methods below to get in touch with the brand Monday through Friday, 9:00 am to 5:00 pm EST:

  • Email: [email protected]
  • Phone: (888)-412-2259
  • Address: NatureM.D.™, LLC, 3515 Naturally Fresh Blvd, Suite 540, Atlanta, GA 30349

Explore your options for health supplements and full-body wellness with these popular brands:

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Article Sources

[1] Hills, R. D., Jr, Pontefract, B. A., Mishcon, H. R., Black, C. A., Sutton, S. C., & Theberge, C. R. Gut Microbiome: Profound Implications for Diet and Disease U.S. National Library of Medicine Nutrients, 11(7), 1613
[2] Conlon, M. A., & Bird, A. R. The Impact of Diet and Lifestyle on Gut Microbiota and Human Health U.S. National Library of Medicine Nutrients, 7(1), 17–44
[3] Hajar R. The Pulse in Ancient Medicine Part 1 U.S. National Library of Medicine Heart views : the official journal of the Gulf Heart Association, 19(1), 36–43
[4] Frumkin, H., Bratman, G. N., Breslow, S. J., Cochran, B., Kahn, P. H., Jr, Lawler, J. J., Levin, P. S., Tandon, P. S., Varanasi, U., Wolf, K. L., & Wood, S. A. Nature Contact and Human Health: A Research Agenda U.S. National Library of Medicine Environmental health perspectives, 125(7), 075001
[5] Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation U.S. National Library of Medicine Nutrients, 10(11), 1564
[6] Bonaterra, G. A., Bronischewski, K., Hunold, P., Schwarzbach, H., Heinrich, E. U., Fink, C., Aziz-Kalbhenn, H., Müller, J., & Kinscherf, R. Anti-inflammatory and Anti-oxidative Effects of Phytohustil® and Root Extract of Althaea officinalis L. on Macrophages in vitro U.S. National Library of Medicine Frontiers in pharmacology, 11, 290
[7] Peterson, C. T., Sharma, V., Uchitel, S., Denniston, K., Chopra, D., Mills, P. J., & Peterson, S. N. Prebiotic Potential of Herbal Medicines Used in Digestive Health and Disease U.S. National Library of Medicine Journal of alternative and complementary medicine (New York, N.Y.), 24(7), 656–665
[8] Kim, J. Y., Park, Y. J., Lee, H. J., Park, M. Y., & Kwon, O. Effect of Lactobacillus gasseri BNR17 on irritable bowel syndrome: a randomized, double-blind, placebo-controlled, dose-finding trial U.S. National Library of Medicine Food science and biotechnology, 27(3), 853–857
[9] Pavan, R., Jain, S., Shraddha, & Kumar, A. Properties and Therapeutic Application of Bromelain: A Review U.S. National Library of Medicine Biotechnology research international, 2012, 976203
[10] Ansell, J., Butts, C. A., Paturi, G., Eady, S. L., Wallace, A. J., Hedderley, D., & Gearry, R. B. Kiwifruit-derived supplements increase stool frequency in healthy adults: a randomized, double-blind, placebo-controlled study ScienceDirect Nutrition Research, 35(5), 401–408

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